Why Is Mitochondrial DNA Important

A mitochondrion refers to organelle enclosed in a membrane, which is found in eukaryotic cells within animals, plants etc. The organelles are not more than 10 micrometers in diameter. Mitochondria, the plural of mitochondrion, are the cellular power plants. Their main function is to supply the cells with ATP or adenosine troposphere, a source of chemical energy. They also help in a number of cell related processes like differentiation, signaling and death. They control cell cycle and growth and are implicated in a number of human diseases and disorders.

Mitochondrial DNA is DNA that is located in organelles known as mitochondria. Mitochondria are structures within eukaryotic cells. They are vital because they convert energy from food into a type of energy that most cells can use

DNA Why Is Mitochondrial DNA Important

Some Mitochondrial Bio-Energetic Enhancers

  • Vitamin B1
  • Vitamin B2
  • Vitamin B3 (Niacin amide)
  • Vitamin C
  • Vitamin E
  • Vitamin K
  • EDTA
  • Coenzyme Q10
  • Idebenone
  • Succinates
  • Dichloroacetate
  • Acetyl-L-Carnitine
  • L-Carnitine
  • PBN
  • N-Acetyl-Cysteine
  • Lipoid Acid
  • Exercise
  • Ginkgo Biloba
  • D-Ribose
  • Creations
  • Taurine
  • Omega-3 fatty acids

Produce adenosine troposphere

Thirteen of the thirty seven genes of mitochondrial DNA are vital for the process of oxidative phosphorylation. The process of oxidative phosphorylation is the metabolic pathway in which energy released during the oxidation of nutrients is used to produce adenosine troposphere (also known as ATP).

ATP is the molecule which is the main energy source for a cell. Almost every type of life on earth has some kind of procedure which produces ATP. In addition to this, mitochondrial DNA is also used in the process of creating transfer RNA (which is also known as tRNA) and creating ribosomal RNA (which is also known as rRNA). These two forms of RNA assist in transforming amino acids into proteins. Thus, mitochondrial DNA assists in two of the most important processes that occur in a cell.

Mitochondrial Energy Production

Mitochondrial energy production is accomplished by two linked metabolic procedures: (1) the citric acid cycle (which is also known as the Krebs, or tricarboxylic acid cycle), and (2) oxidative phosphorylation (OXPHOS).
The citric acid cycle converts biological fuel into adenosine troposphere (ATP). ATP is the body’s principal source for offering cellular energy.

Genetic Disorders

Unluckily, as mitochondrial DNA is awfully imperative, there are a numer of genetic disorders associated with alterations in the mitochondrial DNA. Oftenly, due to different types of cancers mitochondrial DNA will be vulnerable to somatic mutations.

Particularly, mutations in mitochondrial DNA have been seen in different diseases such as breast cancer, colon cancer, and liver cancer. There are four different mitochondrial genes which have also been linked to leber hereditary optic neuropathy. This condition is an inherited form of vision loss.

DNA 1 Why Is Mitochondrial DNA Important

The four mitochondrial genes which have been linked to this condition are given below:

  • MT-ND1
  • MT-ND4
  • MT-ND6
  • MT-ND4L

The mutations which take place in the mitochondrial DNA have an effect on how ATP is generated, and these effects result in minimizing the functioning in the optic nerve.

Mutations in two mitochondrial genes have also been linked to nonsyndromic deafness.Nonsyndromic deafness is a type of hearing loss that is not associated with any other syndromes. The two genes that are mutated and result in this disorder are MT-RNR1 and MT-TS1. These two genes are important in the process of making RNA.

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